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Titel: Drivers of disease severity and burden of hidradenitis suppurativa : a cross-sectional analysis on 553 German patients
Autor(en): Schultheiß, MichaelIn der Gemeinsamen Normdatei der DNB nachschlagen
Grabbe, StephanIn der Gemeinsamen Normdatei der DNB nachschlagen
Staubach-Renz, PetraIn der Gemeinsamen Normdatei der DNB nachschlagen
Hennig, KatharinaIn der Gemeinsamen Normdatei der DNB nachschlagen
Mauch, Melanie
Burckhardt, Marion
Langer, GeroIn der Gemeinsamen Normdatei der DNB nachschlagen
Heise, MarcusIn der Gemeinsamen Normdatei der DNB nachschlagen
Zamsheva, Marina
Schollenberger, LukasIn der Gemeinsamen Normdatei der DNB nachschlagen
Strobel, Alexandra
Erscheinungsdatum: 2024
Art: Artikel
Sprache: Englisch
Zusammenfassung: Background: Hidradenitis suppurativa (HS) is an inflammatory disease of the inverse skin regions with an age peak at around 40 years and an estimated prevalence of 1%. Nodules and abscesses can develop into fistules and scarring, which cause severe pain. HS is a progressive, life-defining disease that leads to physical limitations, inability to work, and social isolation. There is still little data on the drivers of disease severity and burden. Method: The cross-sectional study is based on the baseline data of 553 participants of the health care research project “EsmAiL,” which was carried out as a multicenter randomized controlled trial. It included adult HS-patients presenting with at least three inflammatory lesions and at least a moderate impact on quality of life. Results: Disease activity increases with age. Men are more severely affected than women but feel less burdened. Obesity negatively influences disease activity and disease burden. Affected individuals have a higher level of education than the age adjusted population, but the unemployment rate is significantly higher. Disease activity significantly reduces quality of life and promotes depression and anxiety. Conclusions: HS is a severe and debilitating dermatosis. As a result of the well-established factors involved, HS requires a multi-causal approach to management, in addition to medical and surgical treatment. This must take into account all available therapeutic options, as well as patient education to reduce risk factors and pain, and psychological support. HS requires interdisciplinary and multi-professional care. To prevent disease progression, a structured treatment plan is needed.
URI: https://opendata.uni-halle.de//handle/1981185920/117279
http://dx.doi.org/10.25673/115325
Open-Access: Open-Access-Publikation
Nutzungslizenz: (CC BY 4.0) Creative Commons Namensnennung 4.0 International(CC BY 4.0) Creative Commons Namensnennung 4.0 International
Journal Titel: International journal of dermatology
Verlag: Wiley-Blackwell
Verlagsort: Oxford [u.a.]
Band: 63
Heft: 2
Originalveröffentlichung: 10.1111/ijd.16889
Seitenanfang: 188
Seitenende: 195
Enthalten in den Sammlungen:Open Access Publikationen der MLU